GLP-1 Probiotic

Are there studies that show that GLP-1 can help maintain a healthy weight?
Yes, GLP-1 has been shown to play an important role in metabolic homeostasis and healthy weight regulation. Akkermansia muciniphila and microbial strains that produce butyrate such as Clostridium butyricum can augment GLP-1 production through natural stimulation of the L-cells.  

For a scientific overview of the microbiome, the difference between GLP-1 agonist drugs and microbial approaches to regulating GLP-1, and the role GLP-1 plays in helping to maintain a healthy weight, please refer to the white paper: Harnessing GLP-1 in the digestive tract for better metabolic health. Or click here for PubMed publications on GLP-1.

What clinical studies have been done on GLP-1 Probiotic?
In a consumer study of 274 people taking GLP-1 Probiotic for 6 weeks, 91% reported reduced food cravings. Based on promising findings from this initial consumer study, Pendulum is planning additional clinical trials to further our scientific understanding.

Why did you decide to create a GLP-1 supplement? 
At Pendulum, customers are at the center of everything we do. We recognized there was a need for a natural solution to address cravings and appetite control, and our consumers studies and published research show that the beneficial bacteria strains used by Pendulum are particularly effective in this area.

How does GLP-1 Probiotic compare to other Pendulum products, and which one is right for me? 
GLP-1 Probiotic is formulated with 3 precise strains (Clostridium butyricum, Akkermansia muciniphila, and Bifidobacterium infantis) that specifically target mechanisms needed to upregulate the GLP-1 pathway.

While there is some ingredient overlap in our products, the unique combinations and precise quantities of strains in each probiotic have been specifically formulated to address specific needs.

For example, GLP-1 Probiotic and Akkermansia have the same amount of Akkermansia muciniphila. However, GLP-1 Probiotic is also formulated with Clostridium butyricum and Bifidobacterium infantis which contribute to the production of butyrate. Clostridium butyricum and Akkermansia muciniphila have both been shown to stimulate L-cells to release GLP-1.

Which probiotic is right for you depends on your goals.
If you’re trying to curb cravings → GLP-1 Probiotic
If you’re trying to improve how your body metabolizes sugars and carbs → Metabolic Daily
If you have type 2 diabetes and are trying to lower your A1C and blood glucose spikes → Glucose Control
If you’re trying to improve your gut health → Akkermansia

Need help finding your probiotic? Take our quiz.

Can I take GLP-1 Probiotic with another Pendulum probiotic (e.g. Akkermansia, Metabolic Daily or Glucose Control)?
We don’t currently have the proper data on taking two or all of our products together to provide the appropriate guidance. We recommend speaking with your healthcare provider

Is GLP-1 Probiotic safe?
GLP-1 Probiotic is composed of commensal strains naturally found in the human gut.  These strains have undergone extensive safety studies and found to be safe. 

Can or should I take GLP-1 Probiotic if I’m pregnant?
GLP-1 Probiotic contains commensal bacterial strains that exist within the gut microbiome of healthy people, including during pregnancy. To date, GLP-1 Probiotic has not been studied in women who are either pregnant, planning to become pregnant, or breastfeeding. Please consult with your healthcare provider to see if this product may be a good fit for you.

Are there any side effects of taking GLP-1 Probiotic?
When starting any new probiotic such as GLP-1 Probiotic, there can be an adjustment period. You may experience some gastrointestinal symptoms (increased gas, bloating, nausea, or loose stools) that usually resolve over the initial 14 days or with discontinuation of the product. If you experience symptoms that are severe or do not resolve, please consult your healthcare provider.

How long should GLP-1 Probiotic be taken? 
GLP-1 Probiotic is a daily supplement and can be taken for as long as you experience benefits.

Should someone lower their dose after taking for 60, 90, 180 days? 
To maintain the benefits of GLP-1 Probiotic, we do not recommend lowering the dose.

Can I travel with GLP-1 Probiotic?
You can travel with GLP-1 Probiotic. Just toss your bottle in your bag and once you reach your destination, put it in the fridge if possible since we recommend refrigeration for optimal quality.

What lifestyle habits should someone adjust to maximize the benefit of taking GLP-1 Probiotic?
A diet filled with colorful fruits, vegetables, polyphenols, and a wide range of dietary fibers supports a healthy gut microbiome and will maximize the benefits of GLP-1 Probiotic. It’s also important to maintain healthy stress levels and remain physically active.

Are there certain health conditions that make it harder to maintain a healthy weight when taking GLP-1 Probiotic?
If you have specific health conditions that make maintaining a healthy weight more difficult, we recommend working with your healthcare provider to answer any medical questions.

Will the effects plateau after a certain amount of time? 
GLP-1 Probiotic is designed to help your body optimize GLP-1 naturally and should continue supporting your body’s natural process for as long as you are taking the product.

Yes! Select the option to get reimbursed after purchasing for membership orders, or use the Truemed option at checkout for one-time purchases.
Take a quick 2-3 minute health survey to become HSA/FSA eligible and if approved, you will receive a letter of medical necessity, which you can submit with your receipt to your HSA/FSA provider in order to be reimbursed.
Learn more in our Help Center.