Pendulum Glucose Control, a first-of-its-kind formulation of both probiotics and a prebiotic, is changing the dietary management of type 2 diabetes. This formulation provides specific strains that have been proven to be missing or lacking functionality in people with type 2 diabetes—setting us apart from other probiotics on the market.
Pendulum Glucose Control, a first-of-its-kind formulation of both probiotics and a prebiotic, is changing the dietary management of type 2 diabetes. This formulation provides specific strains that have been proven to be missing or lacking functionality in people with type 2 diabetes—setting us apart from other probiotics on the market.
Research indicates that two imbalances in the gut microbiome are linked to the incidence of type 2 diabetes:
Pendulum Glucose Control is a patented formulation of five anaerobic probiotic strains and the prebiotic inulin, which provides the initial food source for the probiotics. This unique synbiotic helps restore the body’s natural capabilities to produce butyrate, which helps meet the unique dietary needs of people with type 2 diabetes.
Butyrate is the primary energy source for colon cells. It binds to specific receptors within the gut mucosa and stimulates the release of the incretin hormone, glucagon-like peptide-1 (GLP-1). Among healthy people, GLP-1 promotes satiety and reduces appetite, enhances glucose-dependent insulin secretion in the beta cells, inhibits post-meal glucagon secretion, reduces glucose output from the liver, and helps regulate gastric emptying. GLP-1 is deficient in people with impaired glucose tolerance and type 2 diabetes, which contributes to hyperglycemia.
The two main ways PGC works is: It revives body’s ability to produce short chain fatty acids including butyrate, and restores the mucin lining of the gut.
Randomized Double-Blind, Parallel Arm Placebo-controlled
Randomized Double-Blind, Parallel Arm Placebo-controlled
ADCES In Practice Journal
The Therapeutic Optimization of the Gut Microbiota in Diabetes Management
Akkermansia muciniphila
The gut-lining builder
Microbe involved in maintaining healthy mucin layer, which leads to increased diversity within the microbiome and blocks the entry of inflammatory substances into the bloodstream.
Clostridium beijerinckii
The butyrate producer
Microbe involved in acetate and butyrate production. The short-chain fatty acid (SCFA), butyrate, binds to specific receptors within the gut mucosa and stimulates glucagon-like peptide-1 (GLP-1).
Anaerobutyricum hallii
The other butyrate producer
Microbe involved in acetate and butyrate production.
Clostridium butyricum
The digestive health & immunity booster
Microbe involved in acetate and butyrate production.
Bifidobacterium infantis
The digestive health booster
Microbe involved with improved digestive health by way of acetate production and anti-inflammatory benefits.
Pendulum Glucose Control is a synbiotic that contains prebiotic inulin as well as 5 anaerobic microbes known to be missing or lacking functionality in individuals with type 2 diabetes.
At Pendulum Therapeutics, we strive to provide therapeutics to people impacted by a variety of conditions by targeting the microbiome. Here's what's in store.
Ready to set yourself apart from peers and become a microbiome expert? Connect with a group of cutting edge healthcare providers and obtain free Continuing Education Credits.
Enter your email and our Nutrition Communications Team will get back to you shortly.
