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Why are synbiotics important?

Gut microbiome health

Why are synbiotics important?

Why a healthy microbiome needs probiotics and prebiotics.

Filled with trillions of bacterial organisms, your gut microbiome functions best when it has the right balance of bacteria to help absorb nutrients in the foods you eat. A diet high in sugar and fat can fuel “bad” bacteria and possibly even prevent the growth of “good” bacteria. On the other hand, a healthy diet that promotes the growth of friendly bacteria can reduce inflammation and serve as a barrier to harmful germs.

Just like a fingerprint, you have a unique composition of gut bacteria that is based on what you eat, your age, where and how you live, and your genetics. A human’s gastrointestinal tract can host some 1,000 bacterial species. The individual mix of microorganisms living in your gut can impact your risk for certain diseases, including cancer, diabetes, irritable bowel syndrome, and cardiovascular disease.

This is why it’s so important to cultivate a healthy assortment of good bacteria in your gut. But this is achieved by more than just eating healthy foods. To develop and maintain an optimal microbiome, you need to have the right mix of probiotics (bacterial strains) and prebiotics (food for those bacterial strains).

What are probiotics and prebiotics?

You may be familiar with probiotics, which are friendly strains of bacteria found in foods such as yogurt, pickles, and sourdough. They can also be ingested in a pill that contains one or more strains of bacteria.

While probiotics can help maintain a healthy gut microbiome, the important role of prebiotics is often overlooked. Prebiotics help probiotics grow and thrive.

Prebiotics help stimulate the growth and activity of probiotics in your body. Considered fuel for your probiotics, they are typically composed of fiber and can be found in foods such as flaxseed, garlic, asparagus, and chicory root. Because they are found in foods with complex carbohydrates, prebiotics are more able to withstand the journey through the upper digestive tract.

An ideal prebiotic is resistant to stomach acid and other intestinal enzymes. It’s not absorbed in the upper gastrointestinal tract, and it’s easily fermentable by the gut microflora. The same can be said for an ideal probiotic. If it is to be useful, it must survive both gastric acid and bile and make it to the small intestines and colon where it can best flourish.

Because probiotics and prebiotics work together, it’s important to have the right balance of both in your diet to optimize your intestinal microbiome. It’s often recommended that you take them together to get the best results. 

What are synbiotics?

Taking the right mix of prebiotics and probiotics can get a little complicated, which is why synbiotics have emerged as a solution.
Synbiotics are products that have both prebiotics and probiotics. Combining the right prebiotic with the optimal probiotic strains of bacteria creates a synergy that improves the survival and growth of the microflora, especially in the upper intestinal tract.
Because probiotics need prebiotics to survive, it’s important to have the right amount of both.

How can you optimize your gut microbiome? 
Over time, your body may lose beneficial bacteria, which can impact your ability to effectively process carbohydrates, sugars, and fibers, and also absorb the nutrients and enzymes from your food. Eventually, this can affect your blood glucose levels. 

Pendulum Therapeutics has developed a formula that contains targeted strains of good bacteria, along with a prebiotic that helps restore your body’s ability to metabolize fiber and maintain healthy blood glucose levels. A clinical study has shown that in individuals with type 2 diabetes, Pendulum Glucose Control lowered A1C levels and decreased blood sugar spikes after meals.

In addition to five strains of bacteria, Pendulum Glucose Control also contains inulin, a prebiotic that is an essential food for our bacterial strains. In a preclinical trial, we observed that without the prebiotic, there was significantly diminished efficacy of the probiotic strains. This is why it’s important to have a formula that contains both in the form of a synbiotic. It contains several commensal probiotic bacteria strains and the prebiotic of inulin, which is found in chicory root.

The proprietary probiotic blend contains five bacterial strains, including Clostridium beijerinckii WB-STR-0005, Clostridium butyricum WB-STR-0006, Akkermansia muciniphila WB-STR-0001, Eubacterium hallii WB-STR-0008 and Bifidobacterium infantis 100

Learn more about Pendulum Glucose Control now.